Fibro/cymbalta/tramadol seizure/scared

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New Member

Date Joined Oct 2017
Total Posts : 4
   Posted 12/28/2017 4:15 PM (GMT -6)   
Friday I had a seizure and the hospital said it was from the tramadol. I take 600mg gaba 3x a day, I have taken 50mg tramadol no more than 4 times daily for months. 2 months ago my dr added 60mg Cymbalta and then a month ago my rheumatologist doubled that. The trauma from the seizure threw me into a huge flare seemed to have undone all the months of work I have done with my muscles with exercise and acupuncture. I was just reading about serotonin effect and I am kind of worried that I have developed that as I also have severe muscle jerking when I relax or try to sleep. My dr is weaning me from gaba and onto lyrica in hopes of better pain relief and I am not looking forwward to the next few days. I just wanted to know if anyone else has had any issues with any of these combinations. It is possible that I have a lower threshold for seizures as my little brother hs had several and my older brother had a seizure from a medication a little over a month ago. I feel as though the deeper I go on this journey of fibro I only end up with more questions and concerns. I am tired, in so much pain, and scared.

Veteran Member

Date Joined Feb 2009
Total Posts : 851
   Posted 12/29/2017 11:00 AM (GMT -6)   
I did have a seizure when I took the prescribed 3 a day. Now only take one tramadol a day and rarely two Never, ever any alcohol though. That is very dangerous combo.
And on the eighth day God created Golden Retrievers.

Veteran Member

Date Joined May 2014
Total Posts : 2114
   Posted 12/29/2017 11:19 AM (GMT -6)   

Thats a fair amount of meds..we can be med sensitive also..

I can tolerate tramadol in very small doses..i take 12.50 mg at a time.

It helps keeping the edge off my pain..without the side effects..

It was perscribed at a much higher dose, but knowing i am sensitive i take small and see what i tolerate..

We have to know our own bodies..people who are medication sensitive can not handle the same as the average patient..


Forum Moderator

Date Joined Apr 2005
Total Posts : 17646
   Posted 12/29/2017 11:35 AM (GMT -6)   
Sami, go into Fibro 101...the first thread on the forum. There is a link all about Serotonin Syndrome. It's good to be informed...especially if you have more than one doctor prescribing medications. We do have to be our own advocate and we can definitely say NO to medications we are not comfortable taking. I do. We know our body better than anyone. Hopefully you have doctors who will work with you to find the right combination of things.

AND it doesn't all have to be prescription medications. I use ibuprofen with food Tylenol, magnesium malate, vitamin D3, and one prescription medication...a muscle relaxer called be in control of my pain. I walk daily, pace myself and stay as active as I can. Movement really does help.


Forum Moderator/Fibromyalgia

Fibromyalgia, Crohn's Disease, Ostomy, Autoimmune Inner Ear Disease, Diabetes, Osteoporosis, Glaucoma, Scoliosis, Ankylosing Spondylitis
God does not give us a spirit of fear, but of power and of love and of a sound mind. 2 Timothy 1:7
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