I have forgotten what Rockon's original post was about
one day, but anyways, it was where another mast cell patient was suggesting some teas to her. One tea suggested to her was Linden, another Moringa, and hibiscus was the third. Saturday Rockon shared a post about
a Satuday "small business day" discount. That same person who posted about
teas also makes safer body products (like soaps, shampoos, conditioners) and salves, candles etc. (She "coaches" her clients in health/diet, also.) Saturday I was looking at the ingredients on the pictured labels of her sales items and I noticed moringa in something topical. Maybe it was the pain butter but I could be wrong. Rockon has now taken down the sale post or I would be able to tell you. Now thinking about
it, I remembered something in a post about
one of her clients having a moringa tree, and keeping her supplied with all of the moringa that she wants.
At a store that I frequent, everything I see stocked is with moringa leaf, but I was thinking about
looking online for something from the seeds, because I had also found a study about
the moringa seeds.
The tea I tried at a Mexican grocer (and I just saw it at a CVS) was a mix of things. It had Moringa, but I don't know if it was enough to be called therapeutic. This tea's called a Moringa cleanse. I bought a couple of boxes of it and some of Linden tea at the same time. I don't feel any difference using the 2 teas. (by the way, I don't think you're supposed to have whole lot of the Linden? maybe better check on that, if anyone tries it out)
These are all flavonoids, or they have flavonoids, so you're also not supposed to exceed 2000 mgs a day total. Of all flavonoids. Watch out if you're using other things (like turmeric,also a flavonoid.). Rockon has backup for that information, and named several flavonoids, in her thread about
mixing quercetin in oil. At the other forum, if you need the info.
What I did one day was google for: moringa mast cell, on the day I started looking around.
Bioactive Extract from Moringa oleifera Inhibits the Pro-inflammatory Mediators in Lipopolysaccharide Stimulated Macrophages
[LPS = lipopolysacharide. The cell walls of gram negative bacteria have LPS, and will set off reactions by different types of immune cells.]https://www.ncbi.nlm.nih.gov/pmc/articles/pmc4787088/
"Interestingly, we found that M.[Moringa] oleifera hydroethanolic bioactive leaves extract significantly inhibited the secretion of NO production ["NO" is nitric oxide, one of the reactive oxygen species/ROS (free radicals)]
and other inflammatory markers such as prostaglandin E2, tumor necrosis factor alpha [TNF-a, inflammatory cytokines], interleukin (IL)-6, and IL-1β. Meanwhile, the bioactive extract has induced the production of IL-10 [anti-inflammatory cytokine] in a dose-dependent manner."
"In addition, M. oleiferahydroethanolic bioactive leaves extract effectively suppressed the protein expression of inflammatory markers inducible NO synthase, cyclooxygenase-2 [COX-2.The COX's are enzymes that produce prostaglandins] , and nuclear factor kappa-light-chain-enhancer of activated B-cells p65 in LPS-induced RAW264.7 macrophages in a dose-dependent manner."
Rockon could explain to us the relevance of those specific cytokines for our patient group. That is, whether or not those have been found in fibro studies. But since that can't happen, then maybe look at the cytokines listed in the studies in her fibromyalgia/inflammation markers thread if you really want to see if the "moringa cytokines" above are a match to some cytokines found in fibro studies. My brain does not hold onto the cytokine names like her's does
They talk about
prostaglandins a fair bit (inflammatory) in the mast cell groups. For example as I recall PGE2 (above, in that moringa study) is one of the mediators included in the 24 hr urine tests for mast cell diseases. They talk about
prostaglandins causing inflammation and being very responsible for both fatigue and hair loss. I should maybe say that I have never seen reference material given as backup for stating that the prostaglandins are responsible for a lot of the fatigue. Can't inflammatory cytokines do that as well?
Rockon has posted in groups about
luteolin use for fighting prostaglandins. (see the other forum, I think. Look for the quercetin mixed in oil thread?). I am pretty sure that was all brought up in a hair loss thread in a mast cell group one day. But maybe if you don't have mast cell scalp symptoms then I suppose hair loss due to prostaglandin release does not become an issue for you. I am not so sure how that works. Off track, anyways, but it might help someone with that problem to read about
Topical application of Moringa oleifera leaf extract ameliorates experimentally induced atopic dermatitis by the regulation of Th1/Th2/Th17 balance.
Choi EJ, et alhttps://www.ncbi.nlm.nih.gov/m/pubmed/27744247/
There are fibromyalgia and CFS studies with the specific cytokines identified in them, named as being part of each of those 3 different T helper/Th systems. By identifying the cytokines, they try to figure out which Th system is dominating. In these 2 disorders, a TH system has become dominant, which I believe should not happen on a chronic basis. I believe. I am just not as well read on this stuff. And just as likely, I do not remember as much as I would like to, of what I do read.