Hi blue, welcome to the board. Our numbers for those two tests are measured in mg/dL, so it is indeed different here in the United States.. our viral load is measured the same. Am I seeing that number correct? Over 1 Billion? That's very high. I'll try to explain how it got that way for you.
Most Chronic cases are dormant. At some point in their life, their immune system stops working to fight the virus and for some reason, it goes active inside of you. That's the challenge that scientists are trying to figure out, how it goes active and what in the immune system stops working.
In your case, your pregnancies probably weakend your immune system, starting with the first one. When this happened, the virus became active in you and started to increase. Your ALT and ALP are liver function tests. Hepatitis B not only attacks your liver, but also finds it's way into your bloodstream. Since your liver function tests are the numbers they are, which is considered mildly elevated, it can be assumed that you were a chronic case all your life. If this were a recent infection, those numbers would have sky rocketed to over 500.
Viread should be your first and only line of defense. It knocks down the viral load in your bloodstream. Unfortunately, it does not clear the Hepatitis B from your liver as the virus integrates it's way into your DNA so you end up living with it (if it were recent, the chance is 90% that you'd clear it naturally). Over time, your viral load started to probably increase. At some point it may have only been dormant at 1,000 but once it went active, it started to "multiply" inside of you. The longer you remained untreated, the more it kept going.
Once you start taking Viread, you'll notice a great decrease in viral load. However, please keep in mind that if the viral load even reaches zero, you are not cured of it. You will probably end up taking this medication for your entire life or until they find a cure or you are cured of it. The current path of treatment, depending on the person, is 2 years or 3-5 years on Viread and then add on Interferon treatment once it reaches that point and it is undetectable. Hopefully, by that point, they will have released the cure drug :)
Your lab reports are helpful and your doctor did a great thing by making you go on the meds. You need it. Do not get discouraged if your numbers don't decrease within the first month. It's a slow process, but Viread as a 7-10% chance of cure down the road... even though it may take 15 years for some. You are missing some important lab reports, including your Hepatitis B Panel which tells you a little more in regards to whether you have antibodies and whether or not you have the Antigens.
On top of this, you may want to discuss with your doctor the following:
-Fibrotest to detect your Fibrosis stage as well as FibroScan to determine if you have any liver damage (It's a great substitute for a liver biopsy and has given better results, I believe it's available in Singapore.)
-HBsAg in quantitive
-Keep following up with the Ultrasounds
Like you, I am a Hep B sufferer. Did you have any clinical symptoms when you first learned about
it? Most people who were born with it, do not have clinical symptoms and go on living normal lives. If you were born with it already active in your body, which could also be the case, then it's possible that you are just so used to having this and don't realize symptoms.
Also, like you, I suspect I could have gotten it from my mother. I will never know that though as she is deceased, and I only discovered it last year when it was active in me. If it did not come from her, then I suspect from an ex-gf or a dentist needle and I somehow went chronic. I talked to my father about
this and suggested he get tested in case my mother had it, but he is old school too in his 60s. He said he feels fine so no need to check it, plus he doesn't want my step-mom to freak out if she finds out he has it cause she could get it too. Despite my pushing, they want nothing to do with it. Try not to think about
how you got it and worry about
your treatment now!
It's not surprise you were not vaccinated. The vaccine was not available until the 80s.
Post Edited (luckyman316) : 7/22/2014 7:24:49 PM (GMT-6)