Need Help Please Elevated liver enzymes and alkaline phosphatase pre gallbladder removal

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New Member

Date Joined Dec 2017
Total Posts : 2
   Posted 12/4/2017 11:47 AM (GMT -6)   
My wife had an ALT reading of 1929 and AST at 1298 along with Alkaline phosphatase of 211. They did the tests for hep and all came back negative so we had an ultra sound done. They said the gallbladder had a massive stone in it (5cm) and needed removed immediately. So my wife had her gallbladder removed and is still having lots of issues with pain and nausea. As well as trouble breathing when laying flat. Could there be more issues than just the gallbladder she has been in pain for years. Just hoping to find ideas to help her feel better. We have a 6 month old at home and I work fulltime. She may be the strongest women ever but she still needs to get better.

ppm guy
Veteran Member

Date Joined Apr 2010
Total Posts : 1224
   Posted 12/4/2017 9:00 PM (GMT -6)   
Hi Mikey and welcome,
Your liver function should improve after removing the blockage. The nausea and pain should be checked by your dr at your post OP. Your dr can RX you pain and nausea meds.

New Member

Date Joined Dec 2017
Total Posts : 2
   Posted 12/5/2017 7:14 PM (GMT -6)   
Thanks for the reply. I am just really surprised by the really high AST and ALT numbers. I am truly hoping that the gallbladder was the only issue.

Forum Moderator

Date Joined Oct 2010
Total Posts : 4838
   Posted 12/7/2017 8:11 PM (GMT -6)   
Hi Mikey Bjr

I think your wife should get a second opinion on the ALT/AST numbers. Those are high for normal stuff like alcoholic cirrhosis or Hep C, which I am most familiar with.

However, there are other things...gall bladder (which is not an issue now, but there are ducts for bile that may continue to be a problem...check out primary billiary cirrhosis), the pancreas can be a problem, there are autoimmune conditions that make the liver functions go up (Autoimmune Hepatitis), there are conditions that mess with the liver functions caused by too much iron, too much copper, too much tylenol, snake bite, even long ago Lyme Disease can mess with all sort of things.

I recommend you take her to a specialist at a major medical center, a REAL hepatologist, not a GI generalist.

There are meds and protocols for all these things.

Let us hear from you. WE are glad you posed.


Mama Lama
MamaLama, Forum moderator - Hepatitis
Partner received liver transplant (May 1, 2011) FL
Hep C 1a Treatment - Sovaldi/Olysio (March - May 2014)
Undetected since week 4. Undetected 12 weeks post treatment.
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