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Srahammers
New Member


Date Joined Jul 2018
Total Posts : 1
   Posted 7/2/2018 6:56 AM (GMT -6)   
I am new to the forum, and I need some advice . My wife has had stomach flu like symptoms for a week she saw primary care DR and was thought to have the stomach flu and was given nausea medicine and Metamucil for constipation . Two day later things had gotten worse I brought her to the ER they found her liver enzymes were over 4000 and 1600 and had hepatitis they admitted her and thought that the Tylenol she had been taking for pain was the cause they did blood work and she was well within safe limits . They gave her IV fluids and her levels started to come down sent her home two day later and said to follow up with her primary care DR . Less than 24 hr later she is so bad she can’t even walk I take her back to the ER they check her levels again and they have gone back up they admit her back in the hospital and the admitting Dr says the one of the test is back from her first stay and it is positive for cytomegalovirus and that is the cause of her liver problem. The internal medicine Dr came in last night and said that it wasn’t the cause that there was some other underlying condition .He said they have tested for all the common stuff and everything has come back negitive and all other blood work is normal said he was going to start testing for some “weird “ stuff (his words) and may do a liver biopsy . There is no family history of any autoimmune disease or liver problems . What questions do I need to be asking what test should I request . Thank for your help

ppm guy
Veteran Member


Date Joined Apr 2010
Total Posts : 1226
   Posted 7/2/2018 4:44 PM (GMT -6)   
hi Srahammers and welcome,
Has your drs done ct scans or mri? if these, and bloodwork dont show the cause then a liver biopsy would be very helpful. Liver biopsies takes a liver sample and does many tests to determine, if you have excess iron, copper, or diseased liver tissue. it can also determine if autoimmune hep is likely.

When liver enzymes get that high, auto immune hep, and toxins such as Tylenol or other drugs, and supplements are considered. rarely acute onset of hep b, or A can cause very high enzymes. most of these issues resolve on there own in time, except auto immune.

good luck with your testing, and let us know how things play out

MamaLama
Forum Moderator


Date Joined Oct 2010
Total Posts : 4838
   Posted 7/4/2018 4:10 PM (GMT -6)   
Welcome to the forum Srah. If you are near a major medical center and have any concerns about the care your wife is receiving at at community GI practice, be sure to escalate or get a second opinion from a board certified hepatologist who caters ONLY to liver issues.

When my partner, Mike, was very ill, his local GI did not take his symptoms seriously enough and within 6 months he qualified for a liver transplant...he got really sick quickly.

Let us know how the tests come out.

Mama Lama
MamaLama, Forum moderator - Hepatitis
Partner received liver transplant (May 1, 2011) FL
Hep C 1a Treatment - Sovaldi/Olysio (March - May 2014)
Undetected since week 4. Undetected 12 weeks post treatment.

DGinSD
Veteran Member


Date Joined Apr 2007
Total Posts : 850
   Posted 7/18/2018 12:12 PM (GMT -6)   
Sorry I joined this discussion late...Mamalama sent me an email but I was out of town at the time.

While CMV can cause CMV hepatitis and jaundice, they need to biopsy her to make sure it isn't something autoimmune like AIH or PBC - completely different treatment to treating CMV. But to back track...have they run any blood work for the autoimmune conditions? ANA, AMA (for PBC), SMA, LKM1 antibody, and check her IgG levels?
If Tylenol was causing an acute response but she's off and her numbers have risen, then it could have triggered an autoimmune condition.

That's a start. Let us know what's new!

Sorry for the delay...I'm really not on here much since AIH is slow over here smile Feel free to email me separately as well....I'm much quicker on email. The link to my email should be under my screen name.
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