Sleepy, I think the reason you haven't had any answers is because we are not doctors. Each individual is different in his/her reaction to different drugs, even OTC ones, and all drugs have possible side effects. Anyway, I can tell you my own experience:
I have hep C and take both Paxil and Wellbutrin. Paxil dose is 20 mg at night, but I only take half as it makes me too groggy in the morning. I am taking it as an aid to help me get to sleep, not as an antidepressant. Wellbutrin is for depression and I take 150 mg twice a day. I have had no side effects at all from this drug, and it's the only antidepressant I've ever taken that does not cause weight gain in me.
I am not currently in treatment for the hep C, so you really should have your GI doc or hepatologist discuss your options with you. At the time I was taking Interferon, I was not on any antidepressants.