This is from another bb years ago.
"I am trying to understand somethings in relationship to SIBO. "
Okay altered motlity can cause bacteria to enter the small bowel where it should not be really, at least in high counts, because its a pretty sterile environment. For the moment I am just looking at the altered motility reason for SIBO.
What are small intestinal bacteria overgrowth symptoms?
The symptoms of SIBO include:
abdominal bloating and distension,
"A small number of patients with SIBO have chronic constipation rather than diarrhea. "
How does small intestinal bacterial overgrowth cause symptoms?
When bacteria digest food in the intestine, they produce gas. The gas can accumulate in the abdomen giving rise to abdominal bloating or distension. Distension can cause abdominal pain. The increased amounts of gas are passed as flatus (flatulence or farts). The bacteria also probably convert food into substances that are irritating or toxic to the cells of the inner lining of the small intestine and colon. These irritating substances produce diarrhea (by causing secretion of water into the intestine). There is some evidence that the production of one gas by the bacteriaâ€”methaneâ€”causes constipation.
Any Idea what those irritating substances are?
This means these are just in the wrong place and not specific or multiple pathogens?
A "classic" bacterial infection or a reaction to "all" the bacteria there themselves?
I wrote to Dr Drossman on this and here is the reply.
*Any Idea what those irritating substances are?*
sorry its in bold type that is how he worte it into the email so I would see it was his answers.
"IT IS AN OVERSTATEMENT TO SAY THEY ARE "IRRITATING" SUBSTANCES AT LEAST
IN THE SENSE OF BEING SOME TYPE OF TOXIN. THEY ARE NATURAL BYPRODUCTS OF
DEGRADATION OF FOOD SUBSTANCES BY BACTERIA WHICH DON'T NORMALLY OCCUR IN
THE SMALL BOWEL. SO WITH INCREASED BACTERIA IN THE SMALL BOWEL, THE
BACTERIA ARE ABLE TO DIGEST SUGARS FOR EXAMPLE PRODUCING H2 AND CO2 FROM
THE SUGARS WHICH ARE GASEOUS BUT WHICH ALSO HAVE OSMOTIC PROPERTIES,
I.E. INCREASED PARTICLES THAT CAUSE SECRETION OF FLUID INTO THE BOWEL
THUS CAUSING DIARRHEA. IT'S THE SAME PRINCIPLE AS USING NON ABSORBABLE
SUGARS LIKE LACTULOSE OR SORBITAL TO TREAT CONSIPATION BY INCREASING
FLUID IN THE BOWEL. IT'S JUST THAT WITHOUT BACTERIA IN THE SMALL BOWEL,
IT DOESN'T HAPPEN AND THE FOOD SUBSTANCES GET ABSORBED. WITH INCREASED
BACTERIA IT COMPETES FOR THE FOOD SUBSTANCES AND PRODUCES THE GAS AND
*This means these are just in the wrong place and not specific or multiple pathogens?*
CORRECT. HOWEVER, THERE IS GROWING INTEREST NOT IN THE AMOUNT OF
BACTERIA BUT THE TYPE OF BACTERIA. CERTAIN BACTERIA CAN CAUSE SOME MILD
INFLAMMATION OF THE BOWEL AND OTHERS PROTECT THE BOWEL FROM THAT
POSSIBILITY. SO THERE IS "GOOD" AND "BAD" BACTERIA. POSSIBLY WHEN PEOPLE
ARE TREATING PRESUMED SIBO (WHICH MIGHT NOT ACTUALLY BE HAPPENNING,
BECAUSE THE TEST MAY BE INACCURATE) ANTIBIOTICS MAY HELP TO GET RID OF
THE BAD BACTERIA AND THAT MAY BE WHY THEY ARE GETTING BETTER. THIS IS
WHY SOME PEOPLE GET BETTER AFTER ANTIBIOTIC TREATMENT. BUT IT CAN ALSO
GO THE OTHER WAY, I.E., ANTIBIOTICS HAVE BEEN SHOWN TO MAKE IBS WORSE AS
WELL. THE OTHER IDEA IS TO USE PROBIOTICS WHICH CONTAIN "GOOD" BACTERIA
(E.G., LACTOBACILLUS OR BIFIDOBACTERIA) WHICH REPLACE THE BAD BACTERIA,
POSSIBLY REDUCE THE INFLAMMATION AND IMPROVE SYMPTOMS. SO THE ISSUE OF
BACTERIA IN THE BOWEL IS MUCH MORE COMPLICATED THAN SIMPLE SIBO, BUT SIBO CAN BE A PART OF THE WHOLE PICTURE (THOUGH NOT THE WHOLE PICTURE FOR IBS).
In newer research its looking like SIBO doesn't "cause" IBS but that some people have both conditions.
You also have to keep in mind, food allergies and food intolerences don't cause IBS. Some people have more then one condition going on sometimes.
another issue maybe how much fruit you consume.
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