Hi I had constipation severly had to use phospho soda just to be able to go. My doctor prescribed amitiza seemed to work great at first now severe pain in right lower quadrant, belching, gas flu like symptoms, my family doctor told me to go off medication and see if I feel better. Also had elevated lab results on wbc, etc. Will let you know if symptoms go away after discontinueing medicine. Let me know if anyone else has these symptoms. Also ended up in ER doctor said other people had come in with same symptoms who also was on amitiza.