People can get a gi infection. Most people get better from the intial infection.
Some however don't. The infection goes away and a person is left with PI IBS. The infection is gone, but it seems to leave changes in a person.
This is how I developed IBS.
Anxiety and stress are risk factors for developing Post Infectious IBS.
I posted this some years ago to another bb.
I developed IBS from Post infectious IBS when I was ten and am now 50. Probably from e-coli, but they called it dysentary.
I am posting this because I highly believe after tons reading IBS research, this information might help you both. Its also taking me a little bit of time to put it all together for you both.
It is very complex however.
"6th International Symposium on Functional Gastrointestinal Disorders"
"Demonstration of PI IBS as a brain gut axis disorder"
It can be very important in the begining stages of PI IBS to do stress reduction and to calm the brain gut axis. You might have a better chance of recovery. IT is one of the things that can be part of developing PI IBS in the first place.
Chronic stress, which is a threat to the organism either real or perceived, can cause permeability, but more importantly reactive inflammation.
Stress and Disease
Stress, Health and Disease
This is called Psychoneuroimmunology.
The stress system helps fight infections as well as well as its role in stress itself.
In PI IBS they have found an increase of certain important cells. This is complicated and you might want to bring it to the doctor with you perhaps. One of those cells is called an enterochromaffin (EC) cells. The other is called a mastt cell.
Distinctive Features of Postinfective Irritable Bowel Syndrome
"Using conventional criteria, biopsy results for all patients were normal, but there were increased EC cells in the PI-IBS group compared with the non–PI-IBS group (P = .017) and with controls (P = .02). Lamina propria T lymphocytes were increased in PI-IBS (P = .026) and in non–PI-IBS (P = .011) patients compared with control patients, and mast cells were increased in non–PI-IBS patients (P = .054) compared with control patients."
Relative importance of enterochromaffin cell hyperplasia, anxiety, and depression in postinfectious IBS.
The enterochromaffin cells store the majority of serotonin in the gut. "Serotonin is directly involved in initiating the ENS-mediated peristaltic reflex"
There is strong evidence that serotonin regulation from ec cells is a major part of d/c and d/c as well as its role in signaling pain to the brain.
altered serotonin signaling and ibs compilation
Next is the mast cell. The bodies stress system is the HPA axis or Hypothalamic-pituitary-adrenal axis. That can activate mast cells in the gut. Part of that importantly is the fight or flight responce.
"You have two brains: one in your head and another in your gut. Dr. Jackie D. Wood is a renowned physiologist at The Ohio State University. He calls the second brain, "the-little-brain-in-the-gut." This enteric nervous system is part of the autonomic nervous system and contains over one hundred million neurons, which is as many as are in the spinal cord. This complex network of nerves lines the walls of the digestive tract form the esophagus all the way down to the colon. This little brain in the gut is connected to the big brain by the vagus nerves, bundles of nerve fibers running from the GI tract to the head. All neurotransmitters, such as serotonin that are found in the brain are also present in the gut.
Dr Wood has discovered that this little-brain-in-the-gut has programs that are designed for our protection and which are very much like computer programs. They respond to perceived threats in the same way that the limbic system or the emotional brain does. So the threat of a gastrointestinal infection can activate the program that increases gut contractions in order to get rid of the infection. The symptoms are abdominal cramping and diarrhea.
Dr. Wood has determined that a type of cell found in the body and the gut, called the mast cell, is a key to understanding the connection of the big brain in the head with the little-brain-in-the-gut. Mast cells are involved in defense of the body. In response to certain threats or triggers, such as pollen or infection, mast cells release chemicals, such as histamine, that help to fight off the invader. Histamine is one of the chemicals that causes the symptoms of an allergy or a cold. When an infection of the gut occurs, such as food poisoning or gastroenteritis, the mast cells of the gut release histamine. The little-brain-in-the-gut interprets the mast cell signal of histamine release as a threat and calls up a protective program designed to remove the threat â€“ at the expense of symptoms: abdominal pain and diarrhea.
The brain to mast cell connection has a direct clinical relevance for irritable bowel syndrome and other functional gastrointestinal syndromes. It implies a mechanism for linking allostasis and the good stress response to irritable states (e.g., abdominal pain and diarrhea) of the gut. Mast cells can be activated to release histamine in response to perceived psychological stress, whether the stressor or trigger is consciously perceived or not. So the end result is the same as if an infection activated the program in the-little-brain-in-the-gut: abdominal pain and diarrhea."
It is also worth reading my story. Gut directed HT has helped me tremendously and may help PI IBS at the begining stages. Although not a ton of research has been done on this yet with PI IBS a lot has been done on IBS itself, I know in the future it will take place.
Part of this is breaking the vicious IBS cycle before it gets a chance to become embedded in the person. This will also boost your immune system, and reduce pain and attacks.
Ponderings of an IBSer
I personally wish I would have known this a lot sooner in my life.
I am not sure all the links still work, but if they don't let me know.