Thank you all for the info regarding gall bladder removal/bile salt diarrhea/what works and doesn't work!! I had my gallbladder out Feb of 2012. The BS Diarrhea started getting horrible about 8 months ago. My doctor wants me to start Welchol. I've gained almost 15 lbs in the last 9 months and read that Welchol can also cause weight gain. Ugh!!! Im am currently in the process of going off Gluten...I"m also having some hormone changes I think. So much to think about! I just might try the Caltrate minus mag. first, however, Can some shed any light on the difference they have had with Welchol vs cholestyramine? And is it possible to still enjoy coffee after all this?