i have suffered with ibs-c with bouts of ibs-d for quite some time. due to the incredible duration of the illness, i have also developed extreme anxiety and possible depression. this has started to drastically impact my life. i regularly find myself uncontrollably crying and in a depressed, lethargic state. my doctor recently suggested i try zoloft; however, im a bit nervous to go on an anti-depressant. i have heard that it has the potential to make ibs symptoms worse. has anyone used the drug? has it helped with the ibs? what about side effects in general, outside of ibs-related symptoms? i am going to start on a low dose of 25 mg for a week and then move up to 50. any help/advice would be great. thanks!