Prednisone and IBS

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

Regular Member

Date Joined Jun 2007
Total Posts : 60
   Posted 7/28/2007 11:47 PM (GMT -7)   
Hi guys,
       I have been diagnosed/undiagnosed with a very strange case of Crohn's disease over the past 7 years (I'm about to make another post regarding my disease's strangeness... you won't believe me). Several doctors have recently brought up IBS. Now, we have never seen anything definitive of Crohn's disease on any of my tests (3 colonoscopies, 2 GI follow throughs, 1 CT scan, 2 endoscopies) but we have seen some things that suggest Crohn's (Prometheus test) and I have had bleeding (but it could be from a chronic case of hemoroids). That being said, my condition does respond to steroids... that is the pain remains but the D disappears... do some people with IBS have symptoms improve with steroids?

Regular Member

Date Joined Jul 2007
Total Posts : 319
   Posted 7/29/2007 8:03 AM (GMT -7)   
Actually, I was given steroids for a back injury on two different occasions and the one glaring benefit was my tummy responded quite favorably.  The first time I was given the prednisone, I thought it was just my imagination that for a full week my gut behaved like what I imagine a normal person experiences!  I took note for myself but didn't mention it to my doc until a year later, when I had to take the steroid again.  I asked him if it was possible for this medication to have a positive effect on IBS and he did say he had heard such a thing was possible.  Of course, it is not a drug I would ever be willing to take long term because of it's side effect profile.

Forum Moderator

Date Joined Apr 2007
Total Posts : 32602
   Posted 7/29/2007 10:14 AM (GMT -7)   

I tihink that is very interesting.  I don't think you will find very many physicians that would prescribe  Prenisone for IBS. As you said the drug is very potent and the side effects  are serious.

Thanks for sharing the info. I don't have any personal experience with using Prednisone.


Moderator Anxiety ~ Panic Disorders
*~* Not a mental health professional at all *~*
Dx: Anxiety/Panic, Depression 
"If you doubt you can accomplish something, then you can’t accomplish it. You have to have confidence in your ability, and then be tough enough to follow through.” 
~Rosalyn Carter


Veteran Member

Date Joined Mar 2006
Total Posts : 1451
   Posted 7/29/2007 2:56 PM (GMT -7)   
It is used pretty routinly for Crohns so maybe that is really what you have. I have taken it for breathing problems and I have to say that everything in my body feels better when I take it. Intestinally also and I know i don't have Crohns or IBD. I wish I could take it everyday but the side effects long term are too serious. Itold my Dr that I took it for one thing and it seemed to help the stomach and he looked at me like I had 2 heads and said "don't take it for stomach problems" It also can be hard on stomach so you MUST take with food. Frankly at 70 I have reached the point that if it works I do it when I can but I am not as young as most of you. To me quality is not more important than quantity of life.

New Member

Date Joined Nov 2011
Total Posts : 1
   Posted 11/26/2011 10:23 PM (GMT -7)   
I found your post of 2007 regarding your experience with taking Prednisone and how it seemed to help your IBS.
I have had a similar experience, having IBS since the early 1970's, so I know where you are coming from.  Years of colonoscopys, being put on Imuran for about five years, which seemed to help somewhat.  I did notice a distinct improvement after being diagnosed with Hypothryoidism, and being put on Levothyroxine.  My doctor said there was no connection, but since I had IBS for 35 plus years at that time, and boom, suddenly an improvement, I was convinced that there was indeed a connection.  Then for the last five or six years being nearly housebound with increasing IBS symptoms left me nearly suicidal at times.  Then, for an unrelated reason, was put on Prednisone for a five day, 10 tablet dose.  I noticed an improvement of my IBS the following week, and now, three weeks later, the improvement is absolutely astounding, it leaves me amazed.  It is like someone switched off what I have been experiencing for decades. I can still hardly believe it, seems like I have been born again, and I actually can say, "so this it what it feels like to be normal."  For the first time in years I actually can go out to dinner with my family and not spend the evening in the "loo."  So what you experienced with the Prednisone was NOT your imagination.
My annual physical with my doctor is coming up soon, and I have a good feeling that my doctor will blow off my hunch on this.  Has anyone else out there had a similar experience? Side effects or not, I would ask to please put me on another five day dose if these symptoms return.
And no, I do not have Crohns, I have been diagnosed with IBS since 1970's.

New Member

Date Joined Apr 2012
Total Posts : 1
   Posted 4/15/2012 4:21 AM (GMT -7)   
I just started for my allergies. Amazing. Three days of peace. Wow.

Jimbo NZ
Regular Member

Date Joined Mar 2012
Total Posts : 364
   Posted 4/15/2012 2:42 PM (GMT -7)   
I was just perusing this forum but I am usually reading the Ulcerative Colitis forums as that is what I have.

It does not surprise me in the slightest that anyone with IBS responds positively to prednisone (or other cortico steroids) it is a strong anti inflammatory steroid that is routinely prescribed for people with IBD (Ulcerative Colitis, Chrons etc) with varying degrees of success.

I suspect that in many cases IBS and UC and chrons are not clear cut and there is probably a spectrum of irritation/inflamation of the bowel with low end being called IBS and more probnounced being UC. So something that dampens inflamation is highly likely to dampen irritation. I am in no doubt that in most cases people with IBS, UC, Chrons have compromised gut flora which leads to the irritation and inflamation. Steroids will give your system a sledghammer like boost to fight this. However it does have many side effects and is often only a short term 'band aid' as it's not really addressing why your body and bowel have the issue in eth first place. Diet change (removing dairy, wheat, gluten, sugars, caffeine, alcohol - all known to feed bad bacteria or cause irritation) is probably your best bet and at the same time supplementing with a broad spectrurm probiotic.
UC dx in 1999. Living in New Zealand
Treatments tried Pentasa & Asacol (diminishing benefits) Prednisone, PredFoam (effective for symptoms, no sustained remission. Moderately active symptoms over last 4 years.
Currently taking new path via my Holisitic GP. On 200mg DHEA, 2x5mg HydroCort tabs, ProBiotics, Vit C,D&B conc Mineral drops & most importantly GAPS nutrition program - it's working well

New Member

Date Joined Jul 2015
Total Posts : 1
   Posted 11/28/2015 2:10 PM (GMT -7)   
I totally agree with all of you who experienced IBS relief when taking prednisone. However, I only notice improvement when I'm at 20 mg. daily. Less than that and there's no benefit.

Soooooo sorry I can't take it forever. Having relief from the severe bloating, constipation and miserable stomach feeling, even for a short time, was like a miracle. I am depressed to have to go back to the misery.

PS: When Senokot GRANULES were available, I took them daily for 25 yrs. and had NO IBS symptoms. Then they were taken off the market and I've suffered for the past 15 years.
New Topic Post Reply Printable Version
Forum Information
Currently it is Monday, January 22, 2018 5:22 AM (GMT -7)
There are a total of 2,919,977 posts in 320,397 threads.
View Active Threads

Who's Online
This forum has 159440 registered members. Please welcome our newest member, SueB9.
371 Guest(s), 11 Registered Member(s) are currently online.  Details
Bulmanboi123, Dimitri71, tickbite666, Bucko, physedgirl09, 3timechamp, testuser1234, MaryBee1975, Intuition, SueB9, straydog