I have taken Miralax (glycolax -generic version) every day for over the past 2 years!! Of course that is under my doctor's supervision and care. I have read though recently that Miralax is being considered as a long term therapy for IBS-C. Anything that you take OTC that has not been prescribed or recommended by your doctor should not be long term until you get your doc's blessing. That way you can be monitored.
As far as the increased pressure in the abdomen and gas/bloating, yes that will occur in the beginning and I was under the impression that you were taking Miralax on a daily basis. Miralax has to kind of work up in your system so I'm not sure if you are really benefiting by only taking it one day a week. If you take it on a continued therapy, the gas/bloating usually subsides within a week at most.
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Dx: IBS 1989, Diverticulosis 2004, Idiopathic Acute Colitis 2006, UCTD 2007
Meds: Plaquenil 400mg, Chlorzoxazone 500mg, Lyrica 50mg, Protonix 40mg, Lodine XL 1000mg, Klonopin PRN, Miralax 17g, Supplements