hormone replacements

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lifesworth living
Regular Member

Date Joined Jan 2008
Total Posts : 28
   Posted 1/27/2008 7:50 PM (GMT -6)   
hi,everyone ihave been on this med. premarin since 2006 can it make lupus worse?                       sheshe

New Member

Date Joined Jan 2008
Total Posts : 14
   Posted 1/27/2008 7:58 PM (GMT -6)   

Hi Life!

All I can tell you is that within the past 3 months my gyno wanted to put me on hormone replacement therapy. I thought my rhuemy was going to have a stroke when I told her. She informed me that hormone therapy can cause a lupus patient to go into a severe flare. She also said that normally if a gyno wants to put a lupus patient on hormones the gyno and the rhuemy consult each other as to the dosage.

Hope this helps.


PS: I have switched gynos....evidently the 1st one wasn't listening to me when I told her about my other medical conditions.

diagnosed rheumatiod arthritis, raynauds, MCTD 2002, lupus 2007

lifesworth living
Regular Member

Date Joined Jan 2008
Total Posts : 28
   Posted 1/27/2008 11:02 PM (GMT -6)   
hi blurby thanks for the info. i have only been dignosed with discoid lupus all my blood work has been neg. but i have had other things going on and my rheumy did start me on plaqunel. but then he took me off, i have been realy confused with this. lifesworthliving sheshe

Veteran Member

Date Joined Mar 2006
Total Posts : 2608
   Posted 1/29/2008 1:42 AM (GMT -6)   
Hormone replacement therapy is a real controversial subject. I had my uterus and ovaries removed about eight years ago and was put on natural compounded estrogen (tri-est) and it has done wonders for me in many ways. It also helps prevent osteoporosis. I was diagnosed with lupus a couple of years ago and have been in a pretty bad flare for three years and none of the doctors that I've seen want me to stop taking it. I've seen three of the top rheumatologists in the large metropolitan city where I live. I've also consulted with my PCP. So I've been on HRP for eight years and have had lupus for 3. I don't believe there is a connection in my case. Don't you wish medicine were a more precise science.
Lupus, Sjogren's, osteoarthritis, fibro, renauds, restless leg, hiatal hernia, double vision, migraines.
cellcept, neurontin, prednisone, plaquenil, synthroid, triamterene, tramadol, actonel, tri-est, imitrex, cymbalta, multivitamin, calcium w vit D, fish oil, aspirin

Veteran Member

Date Joined Sep 2005
Total Posts : 2573
   Posted 1/29/2008 8:07 AM (GMT -6)   
It depends on the person if hormones will cause lupus to get worse. The thing is artificial hormones can cause an immune response directly to the hormones. Natural hormones can just cause a simple flare if you are sensitive. I would discuss other options than premarin because I have never heard much positive on that- my grandma had everything removed in her late 30's and she had serious problems when they put her on premarin, she has lupus as did/do several other family members.
Dx:fibromyalgia 2002, systematic lupus 2005, rheumatoid arthritis 2006, PTSD 2007, multiple allergies 2005, migraine, compression fractures T11 & T12, Sjögren's, pregnant due May 2008
Tx: plaquenil, Enbrel, Darvocet, Singulair, Flexeril, Baby Asprin,Prednisone, Imuran, Procardia

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