Hello, new member here reading the pericarditis issues. I'm 50 yr old female, completely healthy until one year ago with sudden bladder pain (biopsy shows chronic inflam from I/C) and numerous bouts of pericarditis with thickened pericardium and constant small amount of fluid. Almost every month another episode flares. Also have severe headache (constant with no relief,) fatigue, joint and muscle soreness. All labs are negative (sed rate is 1) ANA and ANCA negative, CRP, etc. This has been going on for 14 months, since Aug 2007. Nobody in Seattle area able to identify cause. I have a very difficult time tapering steroids, having to taper 1/2 mg every two weeks, then go back up again... Steroid withdrawl symptoms almost everyday. Reacted to mtx po, Imuran and Arava didn't work, Cellcept shut down lungs, now injecting 15 mg mtx but can't increase dosage due to sensitivity to medications and onset of severe headache. (Brain MRI shows spots, recommended angiogram with possible biopsy.)
Looking back, I was taking sulfa antibotics for months before becoming ill, lost 25 lbs in 8 weeks, had red petechiae on feet and inner arms, dark purpura on lower legs, raised blood pressure (140/94 from normal 95/70) and increased blood sugars to 135 morning fasting. But nobody put any of these symptoms together and all have now disappeared.
I leave on Sunday for the Mayo clinic in Rochester for cardio work-up and consult with rheumatology. Haven't worked since Christmas, on disability and the LTD did the mandatory SSD paperwork. I just want to feel better and go back to work - If I have a job left...
Anybody had success with the Mayo clinic finding causes for obscure recurrent pericarditis?
Recurrent pericarditis, interstitial cystitis, severe migraine headaches
meds include 18 mg Prednisone, 15 mg methotrexate injected, 400 mg placquenil, colchicine, folic acid, diclofenac, Zofran, Ambian CR, Topamax, Paxil, Rozerem, Vit B-12, Vit D, Riboflavin, magnesium, calcium w/Vit-D, ranitidine, fish oil, acidolophilus, mycelex, nystatin,