It is possible your problems are caused by prednisone but more likely mctd. I have it and it is a complicated disease. When I entered a rehab hospital 2 years ago and was tested for cognitive function I resisted...then I got the results. It affected my short term memory, concentration, ability to cope. No question that there was a neurological impact. The cause...take your pick...disease(s) or meds...or both.
I have also had a profound fatigue which has slowly gotten better as I have recovered. But even now I get tired very fast and sometimes it seems that both my mind and body just shuts down. Fortunately, I am retired and do not have to work.
Even now my short term memory sucks as does my concentration. However, it has improved over the past 2 years.
This is a real, not imagined, problem although the exact cause could be debated with any individual. Call it lupus fog, prednisone haze, or whatever but it is real. It also affected my vision.
Mixed connective tissue disease (systemic lupus, scleroderma, polymyositis), Raynauds phenomena, Hypertension, Barrett's esophagus.
Meds: prednisone 5mg, 50mg imuran, Lotrel 40/5mg, maxide 37.5/25mg, folic acid, potassium, aciphex 20mg, multi vitamins.
Maintain your optimism and you can beat the odds.
"Although the world is full of suffering, it is also full of the overcoming of it." Helen Keller