My sed rate is often really low (2 or 3) even in the presence of obvious disease activity. I've only had my C-reactive protein measured once, but it was 3 or 4 times the upper limit. My dh who is a scientist who researches lupus says that the ESR is an old test, that is subject to lab error and not a reliable indicator of inflammation. It certainly shouldn't (in my opinion) be used to diagnosis or r/o an entire condition.
**SLE since April 1987, age 10 with suspected TIA, neuropathy, joint pain, fatigue. Lupus Nephritis, October 1992, Remission 1993-2000 Major Postpartum flare, 2000-2002, haven't been the same since.**Current symptoms: clotting disorder, vasculitis, joint pain including avascular necrosis in my hip, fatigue, high blood pressure, edema, liver and lung infiltrates, mostly likely caused by the lupus. Meds: CellCept 1000 mg/2x day, Plaquenil 400 mg, Lisiniopril 10 mg, Encora (a prescription Vitamin supplement), Prevacid, 2 x 30 mg day, Xanax ER 1 mg, Xanax .5 mg, PRN, Cymbalta 90 mg, Singluair 10 mg, Zyrtec 10 mg, Potassium Citrate 2 x day. Asthmanex, Advair 250/50, abuterol PRN, Cinnamon 500 mg b. i. d., Flax seed oil 2 x day, lycopene q d. **Chronic anemia, migraines, GERD, Bile reflux, asthma (or lupus induced lung problems), Chronic Pelvic Pain, unexplained infertility x 10 years with one biological miracle son and one adopted miracle daughter!**