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Regular Member

Date Joined Jan 2008
Total Posts : 102
   Posted 4/13/2008 5:59 PM (GMT -6)   
Does anyone wake up in the middle of the night soaking wet? I have been waking up in the middle of the night soaked and I feel as if it is getting worse. My husband says I feel like a salamander sad It's not like a having a hot flash it's more like having a fever and sweating but it's everynight. Does anyone else have this issue. I was just thinking it was my meds.. but Thought I may ask..
SLE, APS, Food Allergies, Gerd, Migrains
Prilosec, zoloft, Plaquenil, asprin, predisone, Imuran, noratriplyine.

Jenny S.
Regular Member

Date Joined Oct 2007
Total Posts : 80
   Posted 4/13/2008 6:52 PM (GMT -6)   
Yes, I have had experience with night sweats too.  My doc thinks it has to do with the Prednisone - I currently take 5mg a day.  Since my last flare has passed, the night sweats have too. 
Hope you get past these bothersome sweats soon.


I have Lupus ... Lupus doesn't have me. 

Dx: Raynaud's(2000)·Lupus(2001)

Rx: Pletal 100mg·Norvasc 10mg·Prednisone 5mg·Plaquenil 400mg


Veteran Member

Date Joined Dec 2007
Total Posts : 2113
   Posted 4/13/2008 7:48 PM (GMT -6)   
I had these everytime I had an RA flare until I went on Pred haven't had one since even with increased RA activity. I always just blamed it on excess immune activity.

Veteran Member

Date Joined May 2005
Total Posts : 7725
   Posted 4/13/2008 9:00 PM (GMT -6)   
Yes, night sweats seen pretty common w/lupus. I haven't every been able to match mine up to a specific activity, time of month, or med -- so my drs & I have decided it is lupus activity. As my lupus is less active, I find I have the sweats much less frequently.

However, there are other things besides lupus that can cause night sweats (body temperature variations) so make sure to mention it to your drs so they can consider it -- they might want to do thyroid or hormone tests.


Lynnwood, Co-Moderator: Lupus Forum

Dx Lupus since '00, new Dr wants to Dx Fibro instead....
SLE(’00), Sjogren's Syndrome, Raynaud's Syndrome, SAD, Depression, Herpes Simplex 1
Piroxicam, Plaquenil, Prednisone, Xanax, Trazodone, Boniva(3mth shot), Wellbrutrin SR, Valtrex
Links: DIAGNOSING LUPUS (4 of 11), LUPUS INFORMATION, LUPUS RESOURCES, Donate to HealingWell, Drug Interactions

Veteran Member

Date Joined Jul 2005
Total Posts : 5403
   Posted 4/14/2008 10:02 AM (GMT -6)   
I had really bad night sweats when I first got sick and would wake up drenched - even my hair was soaked. I noticed that after I had been on plaquenil for a while that the night sweats got much better. Lynnwood is right about telling your doc about this to make sure nothing else is causing the night sweats.
Diagnosis:  UCTD (lupus) 2006; Raynauds 2006; Sjogren's 2006; lupus symptoms began 2003; CFS 1991; Mono 1985
Meds:  Plaquenil 400mg; Prednisone 5-10mg; Tramadol 100mg 3-4x daily; Doxepin 25-50mg; Prevacid; Evoxac; Steriod Cream and Mouth Rinse for tongue and mouth ulcers; Hydrocodone 5/500 prn for severe pain; Artificial tears



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Co-Moderator: Lupus and CFS Forums

Regular Member

Date Joined Mar 2008
Total Posts : 89
   Posted 4/14/2008 2:43 PM (GMT -6)   
I often wake feeling very hot, but not to the point of actually sweating. It's uncomfortable for me though and I often have a fan blowing on me anyway. I am sure Pred could cause it, but I experieced it before Pred.
I'm sorry you are having a rough time of it.

Veteran Member

Date Joined Feb 2003
Total Posts : 5514
   Posted 4/15/2008 7:42 PM (GMT -6)   
Maybe it's not the lupus or the meds at all?  Could it be the onset of menopause?  I don't know your age, so I'm just throwing an option out there for ya! Thinking out loud as they say!
I can do anything through Jesus Christ who strengthens me. I have learned in whatever state I am in,to be content. Phillipians 4:11-13

34 years old. Diagnosed with lupus in 2000. Fibromyalgia, anti-phospholipid syndrome(APS)(stroke),Sjogren's, Raynaud's, seizure disorder-(miraclulously disappeared!), Libman Sach's Endocarditis, vasculitis, sacroiliitis, arthritis (neck) . Prednisone, Imuran, Coumadin, Clobazam, Amitriptyline, didrocal, Cozaar, calcium, Cykolokapron, multi-vitamin, vitamin D, Magnesium, vitamin B6, Acidophilus

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