sulfa drug reactions

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Regular Member

Date Joined May 2008
Total Posts : 30
   Posted 5/7/2008 8:13 PM (GMT -6)   
Hi everyone. I'm new here.  I was wondering if any of you have had reactions to sulfa drugs and what kind of reactions they were.  I have not been diagnosed with lupus yet, but meet a lot of the criteria.  I was on bactrim for a uti. I started running a high fever and had flu like symptoms.  I had this same reaction 3 times before my doc realized that it was a reaction to the drug.

Veteran Member

Date Joined Dec 2007
Total Posts : 2113
   Posted 5/7/2008 8:43 PM (GMT -6)   
I begin to vomit the minute I swallow the stuff and don't stop for hours. I cant take any of the sulfa drugs.

Veteran Member

Date Joined May 2005
Total Posts : 7720
   Posted 5/7/2008 9:01 PM (GMT -6)   
I get a red rash -- small round red bumps -- that sometimes itch and sometimes don' more sulfa-based meds for me!

Lynnwood, Co-Moderator: Lupus Forum
SLE(’00), Sjogren's Syndrome, Raynaud's Syndrome, SAD, Depression, Herpes Simplex 1
Piroxicam, Plaquenil, Prednisone(was 15mg, now 8mg), Cellcept, Xanax, Trazodone, Boniva(3mth shot), Wellbrutrin SR, Valtrex
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Veteran Member

Date Joined Dec 2004
Total Posts : 8198
   Posted 5/7/2008 9:42 PM (GMT -6)   
Hi Aubgirl,
   Welcome to the forum. I found out several years ago that sulfa drugs are bad for me. Sulfa intensifies every symptom to the max for me. I'm glad they figured out what was going on for you. That is on the allergic list in every doctors office I see.
   Good luck and keep us updated. Ask all the questions you want. You will find a very nice and friendly group here. Take care.
Dx: Lupus,RLS,RA,Asthma,Fibro,Sjogren's,Raynaud's,Divertic, Stroke,Atherosclerosis,Seizures,Neuropathy,CAD
JOB 5:18 For he wounds, but he also binds up; he injures, but his hands also heal.

Veteran Member

Date Joined Feb 2003
Total Posts : 5514
   Posted 5/7/2008 11:06 PM (GMT -6)   
I was told from day one of my diagnosis to stay away from any sulfa based drugs.  So I've never taken any.  I have no idea if or how I would react to them.  But it is important to not take any from that family of drugs.
I can do anything through Jesus Christ who strengthens me. I have learned in whatever state I am in,to be content. Phillipians 4:11-13

34 years old. Diagnosed with lupus in 2000. Fibromyalgia, anti-phospholipid syndrome(APS)(stroke),Sjogren's, Raynaud's, seizure disorder-(miraclulously disappeared!), Libman Sach's Endocarditis, vasculitis, sacroiliitis, arthritis (neck) . Prednisone, Imuran, Coumadin, Clobazam, Amitriptyline, didrocal, Cozaar, calcium, Cykolokapron, multi-vitamin, vitamin D, Magnesium, vitamin B6, Acidophilus

Regular Member

Date Joined Feb 2008
Total Posts : 42
   Posted 5/8/2008 9:01 AM (GMT -6)   
I've been allergic to sulfa drugs all my life.  My mother says that, as an infant, I broke out in a horrible rash all over my body when given sulfa medication.    
43 year old female
DX:  Mixed Connective Tissue Disease (lupus, RA, polymyocitis, scleroderma) Jan 08
Meds:  Prednisone 9 mg, Plaquenil 400 mg, Wellbutrin XL 300 mg, Calcium/D 1200 mg, 81 mg aspirin, ibuprofen and Darvocet as needed for pain ( I take it maybe 3x/week) 

Veteran Member

Date Joined Jul 2005
Total Posts : 5403
   Posted 5/8/2008 4:39 PM (GMT -6)   
Welcome to the forum.  You have found a great place for information and for support.  A lot of us have been in your shoes with having a lot of symptoms but no diagnosis.  Unfortunately it can take a really long time for a diagnosis.
I've never taken any sulfa drugs because I was told that a lot of people with lupus have a bad reaction to them.
Take care and I'm glad you joined us.

Diagnosis:  UCTD (lupus) 2006; Raynauds 2006; Sjogren's 2006; lupus symptoms began 2003; CFS 1991; Mono 1985
Meds:  Plaquenil 400mg; Prednisone 5-10mg; Tramadol 100mg 3-4x daily; Doxepin 25-50mg; Prevacid; Evoxac; Steriod Cream and Mouth Rinse for tongue and mouth ulcers; Hydrocodone 5/500 prn for severe pain; Artificial tears



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Regular Member

Date Joined Dec 2006
Total Posts : 102
   Posted 5/21/2008 11:42 PM (GMT -6)   
Sulfa drugs make me soooo nauseous and pukey. This happened YEARS before I had any idea I had something autoimmune going on. So it was interesting to find out that they aren't good for us.
Wife, writer, artist, homeschooling mom to 2 wonderful boys
Lupus (dx May '04), arthritis, PCOS, being tested for vasculitis and Behcet's
Now taking: plaquenil, limbrel, metformin XR, ibuprofen and the occasional percoset for pain

Veteran Member

Date Joined Jul 2006
Total Posts : 831
   Posted 5/24/2008 10:01 AM (GMT -6)   
So being alergic to Sulfur could be lupus. I always thought that my reaction to Sulfur was because my mom would light a match and then blow it out and eat the Sulfur when she was pregnanut with me.

I get reall nervous and it messes with my brain and thoughts when I take it. To the point I don't know where I am or what I'm doing.

DX Fibro 12/31/07   Guess I can put the rest dx
PSTD  Bi Polar 2/04  Depression most of my life  IBS
RX Amitriptylin 25mg
God gives doesn't give us more than we can handle. So this too shall pass.

Regular Member

Date Joined Oct 2007
Total Posts : 185
   Posted 5/24/2008 10:03 AM (GMT -6)   
I had a rash all over my body and really bad on the inside of my knees....... My whole body itched.....
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