I took mtx for about
18 months. At first we tried the pill form (don't remember the dosage) but that did not do much of anything for me. I was then put on weekly injections and it really helped. My energy level noticeably increased and I had increased stamina, too! I was never really able to give up the prednisone, however, so they took me off of the mtx and I have had better results with Arava. Unfortunately, I still need the prednisone to help control my inflammation. (As the others have mentioned, I also took folic acid with the mtx.) I wonder what we will try next? My rheumy also has me on plaquenil and celebrex as well as the arava and prednisone. Like many of us here, you might start to wonder if you should just
open up your own pharmacy!
Good luck with the mtx!
Lupus and RA and LOTS of Medications!