I've been on Plaqunelle for two years now and I am still waiting for the exhaustion to go away. I would think that it is Lupus and not the meds that are giving you grief. I know I get nauseous all the time and I hate it, but I always put it down to Lupus as I know it causes that.
I hope you get some relief soon.
diagnosed with RSD in March of /03, diagnosed with Lupus in Sept./06.Thyroid Disease ,RA
Taking Methotrexate, Plaquenell, Folic Acid, Synthroid,Prednisone, Pantoloc, Singulair, Tramadol, OxyCodeine and extra Strength tylenol when needed,and Zytram.