Hi all - I'm new to the site. Got on here to try to find some answers for my best friend. I know no one can "diagnose" on here, but would a few of you who have had experience in looking at auto-immune disorders take a look at her test results and give your opinions as to what we could possibly be dealing with?
She is 47 years old. Clinical symptoms don't seem to match any one particular auto-immune disorder (pain and tingling in her feet, hands, legs, arms; weakness; fatigue; heart palpitations and pain around the heart; gastritis; heartburn). She does not have dry eyes or mouth, but does have other symptoms of Sjogrens. She has no butterfly rash or skin rash, but does have sun sensitivity in that the sun makes her "flare" worse.
Test results are as follows:
ANA titer 1:1280
Nuclear Ab Pattern: SSA/Ro with SSA > 8.0 and SSB 1.7
RA 77.03 IU/ml (range + >8.9, neg. < 6.5)
Extractable Nuclear Ag Ab < 1.0
Smith Ab < 1.0
Smith And RNP Ab, EIA < 1.0
SCL-70 Ab < 1.0
Double Stranded DNA Ab < 4
Her CBC is normal except for blood cell indices as follows:
RDW 15.9 (this is increased and shows a wide cell size distribution---no manual differential was done however)
Other blood levels that are elevated are:
Total Protein 8.9 (6.0-8.3 nor. range)
Potassium 3.5 (3.6-5.0 nor. range)
Her urine shows positive for bilirubin as well 1+
We may be looking at more than one issue as she had serious gall bladder disease about a year and a half ago and had her gall bladder removed. Because it took the doctors so long to diagnose her though, her pancrease was affected. Her liver functions tests all came back normal, although they did not repeat her amylase or lipase this time. (which still could be elevated)
We would greatly appreciate anyones insight or input. I can't find any sites relating to the Nuclear Ab patterns that would help me differentiate between Sjogrens and Lupus---at least not any that make sense.