Just wanted to tell you that the same thing happened to me. Rheumie ran labs indicating Vit D deficiency, and Rx'd 50,000 units once a week for 8 wks. I only lasted 3 wks before I started having flare problems. I discontinued the mega dose. One year later, another Vit D test indicated even lower levels. This time I went on 1000 mg daily. When re-checking it after two months of that dose the lab ran both tests: OH25 and 1,25. The results were, and still are, confusing. The OH 25 - which as I understand it, relates to supplement intake - was even LOWER (5). But the 1,25 - which is supposed to reflect what the body is making - was out of range high (90's)
I don't really think the rheumie knew quite what to make of it either, but told me to get off the 1000/day. We re-checked it again 2 mos. later (taking no vitamin D) and the OH25 was slightly higher (19) and the 1,25 was down back in the normal range. Since then I've been taking a multiple vitamin that contains 500 mg of Vit D.
Sorry I have no answers - only more questions, really - but at least you know you're not alone in having a reduction in your level after supplementation.
diagnoses: mono 1972; postviral CFS 1997; fibro 1998; CEBV 2005; UCTD (dx limbo) 2007
meds: occasional low dose xanax for sleep, artificial tears w/ ointment at night, ibuprophin (none of which manages the problems very well!)
We cannot avoid the birds of sadness flying over our heads, but we need not let them make nests in our hair.
~~ Chinese saying as quoted by Helen Nearing