From what I read through, it seems that a lot of things can cause us to develop ds-dna and the ds-dna can be active toward different things, like nerves. Whether all of it falls under the heading "Lupus", I don't know. I still can't get them to test mine. They tested my single stranded dna which is useless according to my rheumie because lots of people have it.
These tests also are probably hard to read. I had P-ANCA, but when they tried to confirm and get more info through slit lamp, my ANA was so high it interfered with it. So I guess these things are hard to read.
I hope you get clarity soon. For me, Lupus is not an answer, but just shorthand. I believe there are underlying disease causes for autoimmunity, and through Mayo am getting a lot of help there. But this is just my belief. There are also hereditary factors, but some of us get it and some don't, so there must be a trigger. And it seems once you get one ai problem, you start getting a bunch more, so they need to look at that too.
Ills--Sjogrens-Lupus cond., AI polygland. dysfunction 2, hyper/hypopigment, scoliosis,kyphosis,stenosis, deg.,O.A.,spine surgeries, salivary/lymphectomies, NASH, COPD, RLS, UT/GI bleeds, hystero, brain/nerve damage,TB
Meds--INH,Plaquenil, Evoxac, Metformin, Synthroid, HCTZ, HRT and Lidocaine patchs, Voltaren gel, Klonopin, Vicodin, Restasis, Albuterol, steroids