That was my first symptom. I had a rash that progressed all over my body, swelling of hands, feet, joints, eyes, lips, even my earlobes. I have been tested and retested for everything under the sun. Been told a dx of seronegative lupus (which means it is not in the blood), fibro, allergies, MS, some autoimmune disease, and am presently being treated for vasculitis. As this has gone on for many years for me, I have learned to just go with the flow. If they have me try something and I feel better I am all for continuing.
I have a very understanding neurologist and rheumatolagist that just won't give up on me. I think a good combo of doctors, that believe you is key to getting help.