I have been on sulfasalazine for a few months now. It took a few weeks to notice a difference but I feel better. I was on celebrex before and my doc wouldnt increase my dosage but said to try this. It doesnt work as well as the Celebrex but differently. With the Celebrex my stiffness was almost completely gone, but after about
8 hours it wore off. So I would take it in the evening and wake up stiff again. The sulfasalazine I still have stiffness but to a lesser degree, but its all the time. So like before if it was at a 7 and I took the celebrex I would go down to a 1 or 0. With the sulfasalazine I am constantly at a 3 or 4. I hope that makes sense..... I also noticed that Tylenol doesnt work anymore. I think they work on the same enzymes, so you might need to try ibuprofen. Just thought I would mention that in case you take anything with acetaminophen in it (Vicodin, Percocet, Ultracet, etc.). If you are on a lower dose you might be ok. check www.askapatient.com too. It has first person reviews on drugs. I love it. I check everytime I get a new Rx. Although, some people are like " I took this 15 mins ago and my stomach hurts. Im never taking it again!" Ok maybe it was something you ate...... try it again before you blame the drug!
Anyhow so far as stopping the Plaquenil, my doc tried that too. I was miserable after stopping the Plaq. After about
2 weeks I started getting symtoms I forgot that I had! I also started getting rashes and pain in my hips that was terrible. And I felt like I could sleep 15 hours/day. I stopped for about
a month, and couldnt take it anymore and put myself back on it. I guess it made me realize how much the Plaq does help!
I hope that you have good results with the sulfasalazine! I had no reactions from it. It actually made my stomach feel better. I have been on the Plaq for about
2 years and I still get stomach cramps and loose stools (sorry if that was TMI) from it. Usually when I miss a dose, and double up on it. Since I started the sulfasalazine I can take both pills at once with no problems. Hope that helps give you some insight! And definately check out that website, its very informative.
Dx: UCTD vs autoimmune spondyloarthropathy vs psoriatic arthritis (ie Limbo x5 yrs) Raynaud's, proteinuria
Rx: Plaquenil 400mg, Ultram PRN, Sulfasalazine 2 gram