Hello all - I am in the process of being worked up for a bunch of problems which include numbness and tingling in my hands and feet, bladder hesitancy/retention, pitting edema, severe fatigue to mention a few. I have had a few labs done and being a nurse I was a bad girl and looked at my results before my appointment with my neurologist. To my defense, I have been "work up" for something most of my life and nothing significant has ever come back abnormal. Well this time some have come back positive and now has me a little baffeled. Maybe someone can help me?
ANA by ELISA: detected
ANA by IFA was 1:40 which is a negative titer according to this lab.
Double stranded DNA was 1:160, postive is >1:10
Acetylcholine receptor binding and modulating were increased and blocking was negative.
Sed rate was normal at this time... have had three elevated sed rates in past.
Serum electrophoresis showed slight elevated polyclonal gamma globulin, whatever the heck that means???
MRI of head and back was normal.
All other results at this time are within normal limits.
My question is what is the difference/significance between the two ANA tests and thier different results? And if I have a negative ana but a positive DS DNA, what does that mean in regards to lupus? Also, what's up with the acetylcholine test? Do i have myasthenia gravis on top of all this fun? Any help would be greatly appreciated. I knew I should not have looked, now i am even more stressed then before. Ignorance really is bliss sometimes.
PS - I am new to this posting thing... so please bare with me if I make some terrible taboo. Thanks!