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Debbie Downer
Regular Member

Date Joined May 2009
Total Posts : 62
   Posted 6/5/2009 11:07 AM (GMT -7)   
Quick question for you all- I just found out that my son's IGG is a little low. It was 433. This was discovered through different genetic testing that was done to test for possible reasons for his myoclonic seizures. I can't find a lot of info on IGG that makes sense to me. Is anyone familiar with it. The genetist suggests we see a Rheumotolgist for him. I have for some time suspected that he and I might have a similar medical problem. Does a low IGG indicate auto immune? I am starting to seriously consider lyme disease or maybe he has lupus. He doesn't seem overly fatigued. His symptoms are myoclonic seizures, outburts, ocd, sensory issues. When my husband and I get in an argument and raise our voices at all even a little he gets agitated and starts yelling and screaming and hitting at us. He does this anytime we speak with any passion in our voice even over the phone, not just angry but excited as well. I've never seen any rashes on him. Do you think he should see a rheumotolgist? Should I ask for him to be seen with me at my June 25th appt since I believe our conditions are related? Do they even do that?

Veteran Member

Date Joined Apr 2006
Total Posts : 1334
   Posted 6/5/2009 11:32 AM (GMT -7)   
Here is an article that might help a little.
Don't believe a low number is significant but not sure.  If there is an immune response they would be higher.
They (IVIG) are also given to patients (I had the treatment and it literally saved my life) with various auto immune diseases with very good results.  Not everyone responds and there is some mystery about how flooding the body with antibodies works.  One hyposthesis is that these are "good" antibodies and it helps to reset the immune system and stop it from attacking the body....but researchers are not sure.
Diagnosis of lupus and many other AI diseases is difficult and diagnosis is the result of labs and symtpoms.  Here is a link with typical symptoms.
I would suggest going to a clinic like Mayos, Cleveland Clinic, Johns Hopkins  (don't know where you live but there are a number of clinics associated with major teaching hospitals and universities)...where a team of docs can examine and test your son.  Might not be lupus at all.
You could bring up the subject of your son to the doctor but most doctors are tightly scheduled and they would bill any treatment separately. 
MCTD (lupus, scleroderma, polymyositis).  Diagnosed 2005.  Kidney, liver, GI tract, dysphagia, raynauds, Barretts esophagus, quadriplegic in 2005.  Recovered and now active in skiing, tai, chi, hiking, golf.  Meds: prednisone 2.5mg, imuran 50mg, amlodipine, benazapril, omeprazole, potassium, folic acid, vitamins, maxide and various supplements and vitamins.
Remain optimistic and you can overcome the odds.

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