Posted 6/25/2009 10:57 PM (GMT -6)
My ANA was like that and no symptoms for years. I was told many things can cause that. It was implied that an immune booster I was on exacerbated my positive ANA and mde it worse.
Other diseases can feature a positive ANA, like Hepatitis C and probably many others, but I don't know if its because these diseases tend to cause lupus like syndromes, but usually the people are really ill accordingto my hepatologist at MAYO. He said it is unlikely that a history of mild chronic active Hep C would cause that, more likely I have a genetic predisposition and another more serious illness or event triggered it. I don't know if something like having a positive TB test can cause it. Many people have a positive TB test and don't have TB.
There are many theories about how and why people with autoimmune disease have "dysregulated" immune systems (they atttack our own tissues instead of germs), some feel it is dietary, others feel it is from infections that linger unknown to us when we think they are gone, most believe there is a strong genetic predisposition we have for autoimmunity and that some event (like stress or illness or hazardous materials, etc) may trigger the autoimmunity to start in us.
I also foud out that ANA "glows" which is how they see it. So does P-ANCA and some other common antibodies. My positive P-ANCA could not be confirmed because it could not be distinguished from the glowing of my positive ANA during a slit lamp test, so I don't know that some of these tests are really clearcut.
ANA also goes up and down all the time. The info and advice in the above posts is excellent. And the funny thing is that I can feel like crap and my ANA will be relatively low, then feel great and its high. So go figure. I hope thatyour other test are normal and that its "just the way you are" and not any illness. My ANA was elevated for over a decade and probably longer with no symptoms, then I developed diabetes with NASH and endocrine problems and all of that was still unrelated to my ANA according to my docs. then I developed sjogrens syndrome, a relatively mild form of autoimmune disease. I believe the interferon I took caused my autoimmune disease to become active. I think otherwise I would have continued to havean elevated ANA with no symptoms for the rest ofmy life otherwards.
I hope your doc gets yo info soon. I hate waiting. I hope you can try not to worry. REally, many people have the ANA and never have a problem.
Ills--Sjogrens-Lupus cond., AI polygland. dysfunction 2, hyper/hypopigment, scoliosis,kyphosis,stenosis, deg.,O.A.,spine surgeries, salivary/lymphectomies, NASH, COPD, RLS, UT/GI bleeds, hystero, brain/nerve damage,TB
Meds--INH,Plaquenil, Evoxac, Metformin, Synthroid, HCTZ, HRT and Lidocaine patchs, Voltaren gel, Klonopin, Vicodin, Restasis, Albuterol, steroids