I am an MCTD patient, but have been in complete remission for 3 years (no meds for 3 years -- yea!). A couple of weeks ago I developed red, buring spots on one finger which turned into itchy blisters. They spread to cover the entire finger. An after-hours clinic doc treated it for infection (Doxycycline & Cipro) and the blisters seemed to change...into dry, hardened skin which then peeled in funny waxy pieces leaving some pink wrinkely skin behind. Three weeks later and the blisters are still appearing. They come up gradually and are VERY itchy. Once popped, they dry up and the skin flakes away leaving pink "sclded" lokking skin. Could these blisters be part of my MCTD? Called my Rheumatologist today and the nurse blew me off and told me to call a dermatologist. I surfed online for "MCTD and Blisters" and I see lots of pics that look like my hand. Anyone out there have any experience with this? I am desperate for advice and ideas of how to treat. Or, do I need to go back on my meds (plaquenil and methotrexate...yuck).