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Regular Member

Date Joined Jan 2008
Total Posts : 102
   Posted 8/3/2009 5:29 PM (GMT -6)   
ok so I took my second dose of methotrexate on thursday night only on 10mg right now,and I am wiped out. I sleep all weekend and left work today. Im starting to get a cold. Is this a good sign that the med could working. I truly feel defeated by this med. Any other suggestions.
SLE, APS, Celiac,
 Zoloft, Plaquenil, Asprin, Predisone, Methotrexate, Folic acid

Regular Member

Date Joined Aug 2007
Total Posts : 206
   Posted 8/3/2009 7:43 PM (GMT -6)   
Hang in there. It took a few months for me to adjust to the medicine and for it to start working. I read in another post that you are only taking 10 mg. My dr. started me on 15 and almost immediately went up to 20. At first when I took it I would feel horrible for the entire weekend. I took it on Sat. mornings (never thought to take it at night). I have been on it for almost 2 years now and we are trying a taper (for the 3rd time) I am currently on 5 mg. When I was feeling ill from it I actually had accupuncture done to help with the nausea. I think people with Lupus are really great sleepers anyways and add some pretty toxic drugs to the mix and we are down for the count. I hope you are taking this med with Folic Acid? I take 3 Folic Acid a day and I take vitamin B-6 for energy. I noticed a difference with the B-6 almost right away, which is one of the good things in my life. I have more energy and can usually stay up all day without being so exhausted feeling. Just give it some more time and you will be feeling better soon.
 "Challenges make you discover things about yourself you never really knew."
 SLE and Class II Lupus Nephritis

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