(((((hugs))))) I'm so sorry you are going through this rough time - lupus likes to throw all kinds of nasty curve balls and you never know when they are coming. I agree with Stacie that this could very well be because of your med changes - it has happened to me too. Do call your rheumy and let him/her know what is going on.
Work stuff can be really hard, especially when you have an "invisible" disease like lupus. I quit my job about
3 years ago and I remember there were people at work who were supportive of what I was going through and other people who just didn't get it. I hope you get some relief soon. Take care and keep us updated.
dx: UCTD (lupus), sjogrens, reynauds,
meds: prednisone, plaquenil, methotrexate, tramadol, neurontin,
doxepin, folic acid