What is your diagnosis? Do you have an overlapping connective tissue disease or just lupus?
I have been on imuran for 4 years and had no side effects for 18 months. Then it lowered my wbc, rbc and platelets. It had to be lowered to 100mg, then 50 and now I am only on 25mg and have no side effects. Probably will be taken off it in the near future but there is no rush since I am having no symptoms and no side effects.
There is an increased risk of cancer with imuran. I have had skin cancer 3x (basal cell carcinoma) in the past 2 years. It could be debated that it is just due to spending much of my life in the sun but who knows for sure if imuran had any part. I see the dermatologist every 6 months and have other appropriate and frequent cancer screenings.
MCTD (lupus, scleroderma, polymyositis). Diagnosed 2005. Kidney, liver, GI tract, dysphagia, raynauds, Barretts esophagus, quadriplegic in 2005. Recovered and now active in skiing, tai, chi, hiking, golf. Meds: prednisone 2.5mg, imuran 25mg, amlodipine, benazapril, omeprazole, potassium, folic acid, vitamins, maxide and various supplements and vitamins.
Remain optimistic and you can overcome the odds.