I have ana negative lupus and sero negative RA. As long as you are getting treated for the symptoms a dx doesn't matter. Trust me a dx can be bad when it comes to insurance. So until and unless you file for disability worry less about a dx and more about effective treatment. That is not to say that having the correct dx would not be nice but I am just saying sometimes knowing isn't all it's cracked up to be. I would ask about the mtx not helping to see if you could try a different treatment. Are you on plaquenil? it is usually one of the first treatments tried with lupus but takes 6 weeks to 6 months or more for full benifits to show up and because it happens so slowly we often don't realize how much it has been helping until we give up on it. I ask about plaquenil because it can help with fatigue. I also suggest asking about provigil and nuvigil which are both medications to help with fatigue. I really hope your doctor gives you more answers today.
Dx:fibromyalgia 2002, systematic lupus 2005- definate CNS involvement dxed late 2005, psoriasis 2006, rheumatoid arthritis 2006, PTSD 2007, multiple allergies 2005, migraine, compression fractures T11 & T12, Sjögren's, damaged periphrial nerves 2007, exema
Tx: plaquenil, Enbrel, Tramadol, Singulair, Skelaxin, Baby Asprin, Imuran, Prilosec, lasix, Evoxac, Celebrex, Darvocet when things get too bad, prednisone again, various vitamin/mineral supplements, cozar
"Those who dream by night in the dusty recesses of their minds wake in the day to find that it was vanity: but the dreamers of the day are dangerous men, for they may act their dreams with open eyes, to make it possible." T. E. Lawrence