Yep, that's one of the first questions. I teach nursing, and now we look at a fever as a good thing, the body's first natural defense against a foreign, disease producing, invading organism. We teach that a fever needs to be assessed in view of the pt's. normal, healthy, baseline number. So that a person with a normal temp for them of 96, could indeed have a fever at 98 or 99. But, many of our meds are immunosupressive, which can stop our body from recognizing, (on an immune system response level), the infection, so then the immune cells don't tell the brain to shiver and shake the muscles to directly add body heat to heat up the blood, which is then evidenced as a fever. So, people on prednisone, NSAIDS, cellcept, etc. have to be extra vigilant about signs of systemic illness, and see the dr. asap.