about to go get my first shot of methotrexate

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Regular Member

Date Joined Aug 2009
Total Posts : 43
   Posted 4/13/2010 12:17 PM (GMT -7)   
so nervous!!! i had a bad reaction to the methotrexate pills (severe nausea/vomiting for 10+ hours) so i'm mostly scared of that happening again. my rheumy says the nausea shouldn't be as bad with the intravenous form.

can you share your experiences with methotrexate and nausea/vomiting? how long does it typically last and what do you do to make it better? last time i felt like my insides were being ripped out...

also, since methotrexate interacts with NSAIDS... what do you take instead on a daily basis for pain?

thanks for the help,
23 years old w/ sle, sjogren's, raynaud's, pernio
meds: plaquenil, prednisone, nifedipine, pentoxifylline, paroxetine, zolpidem
supplements: iron, vitamin D, omega-3, biotin
starting methotrexate 4/14... wish me luck!

Veteran Member

Date Joined Oct 2004
Total Posts : 2244
   Posted 4/13/2010 5:29 PM (GMT -7)   
I hope you tolerate the shots well. I have been on MTXS for over 2 years now and do very well at my current dose. We tried increasing it once and it made me very sick so I imagine if we ever had to increase it then I would end up on the shots too :(

I am on a daily NSAIDS and have been for years. My current dose of MTX is 7.5mg maybe you are on a higher dose than me and that's why you can't take the two of them together. Let us know how it goes! Take care
Trust in the Lord with all thine heart, and lean not unto thine own understanding ~ Proverbs 3:5 ~

DX: Lupus, Sjogrens, Raynaud's, Hashimoto's and Celiac Disease
RX: Imuran, Plaquenil, Methotrexate, Flexeril, Piroxicam, Levoxyl, Folic Acid and Tramadol (as needed) and magic mouthwash ( as needed for mouth sores)

Veteran Member

Date Joined Dec 2006
Total Posts : 2818
   Posted 4/22/2010 7:14 PM (GMT -7)   
Hi Kim, If you are out there reading posts I would like to know how you did with the methotrexate. If is always good to hear from experiences. We never know when we may have to deal with the same situation. I hope you were able to do well with it and that it helped you out.
nexium,temazepam,predisone,plaquenil,propanalol,effexor,citracal,pottasium, vitB,iron,xopenex,advair,spirivia
You learn to love and live
you fight and you forgive. 
you face the darkest night.
just live before you die.

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