Speckled ANA Reading - Lupus or just Ulcerative Colitis?

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Regular Member

Date Joined Jun 2010
Total Posts : 31
   Posted 6/15/2010 7:26 AM (GMT -6)   
Hi guys.
I have had ulcerative colitis for 6 years.
I hurt my leg late last year and it took 6 months to heal when it shouldn't have taken any longer than 6 weeks, which got the doctor to do some blood tests.
3 months ago (and while my colitis was under complete control) I had a speckled ANA reading of 1:1200.
Since then my colitus has flared up and I had another blood test resulting in an ANA reading of 1:2500
My doctor seems to think that the ANA reading is completely and wholly linked to my ulcerative colitis. My colitis specialist thinks that they're completely unlinked.
What do you think? What should I do now?

Veteran Member

Date Joined May 2005
Total Posts : 7723
   Posted 6/15/2010 7:48 AM (GMT -6)   
Here are some excerpts from a longer article found in the 1st thread
Lupus Resources said...
- A titer above 1:80 is usually considered positive.
- The speckled pattern is found in SLE and other connective tissue diseases

Because the ANA is positive in so many conditions, the results of the ANA test have to be interpreted in light of the person's medical history, as well as his or her clinical symptoms. Thus, a positive ANA alone is never enough to diagnose lupus. On the other hand, a negative ANA argues against lupus but does not rule out the disease completely.

A Positive ANA Does Not Equate to Having a Disease
The ANA should be looked at as a screening test. If it is positive in a person who is not feeling well and who has other symptoms or signs of lupus, the physician will probably want to conduct further tests for lupus.

If the ANA is positive in a person who is feeling well and in whom there are no other signs of lupus, it can be ignored. If there is any doubt, a consultation with a rheumatologist should clarify the situation.
If the colitis specialist thinks the ANA is not related to colitis, it might be a good idea to see a rheumotologist -- they're the lupus (and auto-immune disease) experts.

Hope that helps,
Lynnwood, Lupus & Sjogren's Moderator
"Life is far too important to be taken seriously" - Oscar Wilde

Regular Member

Date Joined Jun 2010
Total Posts : 31
   Posted 6/15/2010 3:07 PM (GMT -6)   
I also get sick frequently catching EVERYTHING that goes around, and always have
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