I have been on CellCept for about 14 months (name brand for the first 3 months and generic since then). My prescription was (and remains) two 500 mg tablets twice a day. When I first started I had the same reaction as you describe. So my rheumy had me back off to one tablet once a day. He had me increase the dosage each week (took about a month) until I was at full strength. That seemed to do the trick. But I do take it on a completely empty stomach (at least two hours after eating and one hour before eating). I do not know if taking it with food would cause a different reaction or not. Once I adjusted to the medication, it really helped my lupus symptoms. Hope you feel better :)
Take care, Fran
Dx: Lupus, sjogren's, celiac, severe allergies.
Daily Meds: Plaquenil, Zyrtec. Aciphex, Nasacort, Prozac, Ambien CR, CellCept, Bactrim, Zantac.
Daily Supplements: Calcium, B-100 Complex, Daily Vitamins.
As Needed Meds: Epinephrine, Benadryl, Proventil, Xopenex, Tylenal, Darvocet, Prednisone.