I am on the verge of starting to take it. I have been on prednisone far too long, and it was suggested as a safer alternative to the high dose tapers I am forced to take for my ashma, and the 5 mg. maintenance I have lived on for my neuro symptoms. Both my neurologist and rheumatologist have encouraged me to do so, as I was staying at a high level of sick, in a flare that wouldn't quit. The doc was about to write the prescription, but I put it off for 6 more months because, for the first time in my life since I was 11, I am no longer working, and hope that being able to rest more might send my lupus into remission without either prednisone or cellcept. I did alot of research and networking, and am reassured that it's benefits will outweigh the risks. I was impressed that both drs. said the side effects were really not that bad and it seems it's efficacy in autoimmune disease is being actively studied. I plan to call the dr. after Christmas. My health insurance is really good, and my HMO plan will cover the generic form for our $10.00 copay for a 105 day supply. I think the cost is coming down, because it is on the list of standard priced meds from our drug providers. We get almost all of our prescriptions through Medco.