Yes, prednisone can cause fluid retention! I had a ton of it when I was on high doses!!! Have you had your blood work checkded since the fluid has started? If not, I would ask to get your kidneys checked to be on the safe side but since you are on pred, i would pretty much think it was from that!!
Kidney Diseases & Disorders and Lupus Moderater
Cyclosporine, Prednisone, Lisinopril, Mobic, Vitamin D 50,000 units
PRN: Imitrex, hydrocodone, Ambien, Flexeril, Ultram,
If God brings you to it, he will get you through it!!