I have been through the rigamaroo. Chronic fatigue syndrome, EBV, autoimmune disease, Lupus, Fibromyalgia, Myofacial pain syndrome, and now MS or mixed connective tissue disease. Still waiting to see a rhematologist. I will be happy to get the autoimmune diagnosis back, I have been sick for way too long not to have treatment. I've responded to antimalarials but it only lasted for so long, and that was that. The autoimmune disease can make you sick everyday, very bad sick, for me, the difference in the flare is that I am bedridden and I cannot make myself do anything. Alot of days, I don't do much anyways, but at least I stay out of bed. I could not manage through life right now without neurontin and toradol. Narcotics just make me vomit. I loved duragesic pain patches at one time, but my tummy couldn't handle it anymore. I haven't tried prednisone yet, but more than ready to. I love PT too, but you can't go constantly. My doctor offered to get it for me in home, and tell a little lie that I was so sick I couldn't drive, but I told him no. He diagnosed me with fibromyalgia but he doesn't take any of my symptoms seriously, and that's hard when your having serious pain and no one will do anything. No one believes I'm sick because of that diagnosis. My ANA is high, I have mixed patterns, and my RNP is high. I don't fit completely into the criteria for mctd or ms, but maybe I'll get lucky and find out it's one or the other. I need to know what's really wrong. Don't want them playing a guessing game with me anymore. Thanks & I live in west virginia.