Plaquenil seems to have a good reputation, I researched it after my new rheumy prescribed it even before he wrote lupus as a diagnosis. He said it is preventitive for down the road and prudent to give it even before lupus has been ruled in. I was so very sick, and then, within a week, yep a week, I felt better. I have a cousin who is a pharmicist. GI distress seems the biggy, but for me, Plaquenil and Neurontin were a miracle cure. They kept me working at a job I loved for over 5 years. My hair was being lost d/t Hashimoto's and I have an iron gut. So a vague and brief nausea and occ. diarrhea was worth the lessened joint pain. Neurontin really helped the burning and tingling in my extremities. I don't ever want to stop taking it. On a funny note, I havent had a mosquito bite since I started it. They will land on me, stick in their probiscus thingy, taste........ and leave. No bumps no redness and my rotten husband says........hmmnnnn
ps. my rheumy is really strict about the eye damage risk, and I see an eye dr. for medical exam every January before he will send in the new prescription.
God knows, even if I don't....
CNS Lupus 2005, APS, Hashimoto's Thyroiditis, Degenerative Osteoarthritis, Asthma
Meds: Plaquenil, Neurontin, Thyroid, meloxicam, Aspirin, Atenolol and Norvasc, Prednisone 5mg daily. (20-40mg prn), Vit. B12 2400 mcgs, Vit D 1000U and Ambien every night. Advair, Albuterol and DuoNeb inhalers.