ANA quantitative vs. ANA IFA

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lucysgd
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Date Joined Jun 2008
Total Posts : 675
   Posted 9/1/2011 8:53 PM (GMT -6)   
I've looked this up and still don't understand.  It was said the ANA IFA is the "gold standard" test.  But the result is simply positive or negative.  So it sounds like it's used to verify the quantitative, which actually gives dilutions and patterns. 
Can anyone explain this to me?  Both of mine are positive, but I don't understand (and would like to) the meaning of the IFA and why it is done after the quantitative.   Anyone?
Thanks.
 
 

couchtater
Elite Member


Date Joined Jul 2009
Total Posts : 14475
   Posted 9/2/2011 6:02 PM (GMT -6)   
IFA, if I understand it correctly, tells what kind of pattern is seen under special examination. this is further clues as to which kind of autoimmune disease you have. The titers is subjective due to different labs standards.
Joy

lucysgd
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Date Joined Jun 2008
Total Posts : 675
   Posted 9/3/2011 3:50 PM (GMT -6)   
Thanks Joy - guess the old brain was processing backwards..... in the fog....

Bsime
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Date Joined Apr 2006
Total Posts : 1344
   Posted 9/4/2011 1:29 PM (GMT -6)   
Lucy,
 
ANA IFA is the qualitative part of the ANA test and determines the pattern which makes the results more specific to various diseases.  ANA will tell you that something is going on but not which of the several possible diseases is active. 
 
 
Bill

lucysgd
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Date Joined Jun 2008
Total Posts : 675
   Posted 9/5/2011 11:15 PM (GMT -6)   
Thanks, Bill, for the response and the link.   I've been having some new symptoms/problems lately, and looked back at my old tests for the patterns - which were Nucleolar and Speckled. .   Is there a rule of thumb on the frequency of other tests for things like MCTD, scleroderma, etc. based on the pattern?  I've had nothing checked for over 1 1/2 years beyond ANA/IFA and RF.

Bsime
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Date Joined Apr 2006
Total Posts : 1344
   Posted 9/6/2011 7:25 AM (GMT -6)   
Tests depend on your symptoms and what meds you are taking.   Your doc will not continue all the tests used for diagnosis just ones needed for monitoring your disease.  CBC, CMP, cpk, sed
 
 
Bill

lucysgd
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Date Joined Jun 2008
Total Posts : 675
   Posted 9/7/2011 12:26 AM (GMT -6)   
Thanks again, Bill.   Appt. coming up - will see what can be pinpointed, if anything.
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