There are 3 "big guns" that rheumies usually try with LUPUS patients, as we all react different to each one. Lupus is mysterious enough that it's mostly a trial & error experiment, no way to know which if these might work best for an individual patient.
These are Cellcept, Imuran and Methotrexate (MTX)
. Each of these has some rather serious side effects possible -- but remember if it happens to even 1 person out of a 500 person trial they have to list it. If you have a strong preference as to what order you want to try these in, talk to your doctor -- although you might get different results depending on doctor, country, etc -- not all drs are very flexible.
I know Lupus patients who have had good results with each of these 3, others who have had no results from the same 3, and any other combination you can think of. Which order to try them in is usually just up to your particular doctors opinion.
For me, I started with Imuran for 6 months -- it did no harm, but didn't seem to help any either. Then we tried Cellcept - for me, this was my miracle drug that saved me from serious cognitive dysfunction and seems to have sent my Lupus into a 'quiet' state. I'm now off of Cellcept, even off of Prednisone, and am maintaining well on Plaquenil.
Also, note that the previous post about
MTX being the 'king' doesn't have any references to indicate whether it came from a scientific journal or personal opinion, and that it refers to how MTX works with RA -- RA is significantly different than Lupus!
Feel better soon!
Lynnwood, Lupus & Sjogren's ModeratorDIAGNOSING-LUPUS & LUPUS-RESOURCES
"Life is far too important to be taken seriously" - Oscar Wilde