I haven't noticed any difference. Of course, I live in Florida, so maybe it doesn't count!
I alternate between UPF 50 clothing, sun umbrellas, and sunscreen, depending on the time of day I go out and whether I expect to be outside long. I hate the slimy feeling I get from the sunblock, so I often wear a UPF 50 hat, scarf, and gloves over my regular outfit, to good effect. I also have been slowly building up my closet with UPF 50 clothing - dresses, pants, shirts, etc.
I keep joking with my folks about moving to Forks WA, LOL.
dx: SLE 07/2011, OCD 2006, osteoarthritis 2002
rx: CellCept 2,000mg/day, NSAID for pain, zoloft 200 mg