High ANA questions

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New Member

Date Joined Sep 2013
Total Posts : 4
   Posted 9/11/2013 2:33 PM (GMT -6)   
Hi! I am 31 and have never had any major health problems until recently. First in 2010 after my daughter was born I had some joint pain and strange bruise-like spots. I had some blood tests at my ob office and cbc and CRP was normal. I chalked it up to hormones and eventually felt better.
My son was just born in Jan 2013 (7 months ago) and the joint pain started again. My knees hurt at first, but now it's my ankle joints mainly and sometimes my fingers. I get the bruises again. I have slight pitting and onycholytis in my fingernails, tingling/tightness feeling in my left foot and forearm, and I don't seem to be able to lose weight. I weigh the exact same since my son was born...whether or not i eat right and exercise. That could be due to getting older, bc my tsh was normal.

I saw a rheumatologist a few weeks ago and am waiting for my followup appt. All i have now is my lab results and a few emails back and forth with the dr. My mom has MCTD...(scleraderma, raynouds, polymyositis) but is in remission now. She loves this dr.

CBC- normal except MPV being a tiny bit high
ESR - 26 (should be less than 20)
CRP and CK- normal
CMP- normal - Calcium was 10...within range but seemed high to me
Vitamin D - 30 ( i take 5000iu a day due to being low in the past)
HLA-B27 - negative
ANTI CCP - <17
RF-S - 11 (<14)
most concerning to me is the
ANA - 1:640 speckled
ENA - negative ( no values ...all <20)
DNA - negative at 1:20
complement 3 and 4- normal

Also...i was getting over a sinus infection at the time of this bloodwork. Dr says it could have caused higher sed rate.

so...the dr. doesn't seem to be worried at all. He says whatever is going on is very minor and there are no signs of harm to my body. I really don't want medication, as I breastfeed my son. I just have slight pain anyway...
my concern is what does this mean for my future?

Any ideas or similar situations?
Why is my ANA so high alone?
Could it be my thyroid? he didn't check it.

Please help. I am so anxious about all this.

Post Edited (danzergurl00) : 9/11/2013 1:37:11 PM (GMT-6)

Elite Member

Date Joined Jul 2009
Total Posts : 14475
   Posted 9/11/2013 2:47 PM (GMT -6)   
You maybe just a very mild case since your pain isn't too bad or it could be fibromyalgia.

I'd wait and see if I get worse or the doctor gets concern.
Lupus, Fibromyalgia, Glaucoma, Asthma, Hypothyriodism, Sleep Apnea, OA, Depression, and Allergies

When life throws you lemons....
Pick them up and throw them right back at them! :))

Veteran Member

Date Joined May 2005
Total Posts : 7723
   Posted 9/11/2013 3:01 PM (GMT -6)   
Since your mother is now in remission using the same Dr, it seems reasonable to me to wait and see what the Dr says/does at your follow-up appt. That it, it sounds like you have a trust-worthy Dr.

Even if you do have Lupus or another auto-immune disease, symptoms are not the same for any 2 patients...so where you are now really has no bearing on where you might be in the future.

Worry just robs you of time you could be enjoying today, and stresses you out. Stay and enjoy today - tomorrow will be whatever it is and anxiety etc will only make everything seem much worse than it is.

Be well!
Lynnwood, Lupus & Sjogren's Moderator
"Life is far too important to be taken seriously" - Oscar Wilde

Barbara Lee
Veteran Member

Date Joined Sep 2003
Total Posts : 2889
   Posted 9/11/2013 10:20 PM (GMT -6)   
Hi there just wanted to say I agree with what Lynnwood had to say, worrying can make things worse and make life more difficult.

My daughter has always had a positive ANA at 1:640 just like yours. She started testing positive at age 10 or so, she's now 20 her last test was negative. She's never had many symptoms and she has been seen by a Peds Rheumy and my Rheumy.

It's been said that you can have a positive ANA if you've been sick. With what symptoms you are having I really wouldn't worry to much at this point. Like Joy said you may have Fibro it's really hard to say. I had a hard time dealing with my daughter's ANA being positive and me being so sick with lupus. I was certain she had to have it. That's just not always the case. I'm sorry your Mom has MCTD but glad she's in remission.

Try not to worry to much, enjoy being with your new baby boy and just keep an eye on things. If you start having more issues go back and have the Rheumy check you again.

Good luck and best wishes to you.

DX- RA, Lupus, Fibro, LGL Leukemia, Pulmonary Hypertension, Bells Palsy, Gastroparsis, Blood Clots, Glaucoma, Chronic Pericarditis & Pleurisy, Severe Anemia. Way to many medications to list.

Veteran Member

Date Joined Jun 2008
Total Posts : 675
   Posted 9/12/2013 1:22 AM (GMT -6)   
I started down this path with a very similar profile. High side ANA with speckled/nucleolar pattern. Sed rate at 20 and high CRP - with remaining labs pretty much normal. I was started on Plaquenil because of severity of symptoms and have now been on it for 4 yrs with a dx of UCTD. I agree with everyone that your rheumy seems to know what he's doing and I wouldn't worry either, at this point. I am 20+ years older than you

However, I noticed you said your calcium was at 10 - which you felt is a bit high. If it stays up and/or rises, I would be sure to ask for a PTH count (parathyroid hormone) when you get your next labs. If your calcium is high, your PTH should be very low (sleeping). I'm just finding out about this - there are correlating symptoms if the PTH/calcium ratio are out of whack (fatigue, muscle and joint pain, etc.) My PTH and calcium were both considered high with most recent labs, and I was referred to endocrinologist to investigate. Still awaiting results. But the endo also said that an infection could affect the calcium level, and I had a UTI at the time of testing.

Parathyroid.com is (over) loaded with info on the subject of hyperparathyroidism. I only mention this because PTH is not something commonly tested, and the problem could be easily missed, though hyperparathyroidism is not common at your age. Best of luck - Lucy

New Member

Date Joined Sep 2013
Total Posts : 4
   Posted 9/12/2013 12:00 PM (GMT -6)   
Thank you all for your advice! i really appreciate it.
It's wonderful advice not to worry. I really need to work on that and enjoy the moment i'm in. I have 2 little ones and feel like i've been so distant lately with all this anxiety i'm having.

I do feel like the rheumatologist knows what he is doing, so I guess I will just have to trust him and go back if things change in the future. He did say he will follow me infrequently.

I will check into the parathyroid thing... I actually have been on that website you mentioned on my quest to figuring out what is wrong. I think i'll have him check everything concerning thyroid when I go back... just to make sure.

Thank you all again!
God Bless!

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