Yes, there are many cross-over symptoms between Lupus, Lyme, Allergies, and many other diseases. I have also posted on the Lyme forum recently because our son was diagnosed with Lyme. I have had symptoms of Lupus - fatigue, achy joints, the butterfly rash, and ANA test at 1:1280. Only my dermatologist ever felt confident in diagnosing Lupus, but after learning more about Lyme, mold and other toxins, I wonder....
I would advise anyone with the cross-over symptoms to investigate Lyme further. Our son was diagnosed at Sponaugle Wellness in Florida, had 7 weeks of treatment, and is now a different person.
Our research is showing us Lyme is much more prevalent than we ever realized, and that it is an extremely dangerous disease that can be fatal. We have also learned that it is not only contracted through ticks, but mosquitos, horses, and even sexual contact!
Lyme is hard to diagnose through tests that regularly show false negatives. However, there are tests that are more accurate, and there ARE Drs. who are experts in the disease. I now believe we have thousands of people diagnosed with things like Parkinson's, RLS, IBS, psychological conditions such as depression and Bi-Polar disorder, who are never correctly diagnosed, never correctly treated, and therefore, their symptoms continue to worsen!
Western medicine has a problem with things like "chronic lyme" but when you see people's health improve, quickly and dramatically, you have a hard time not believing it.
So, for my two cents worth, and in my own opinion, I would suggest consulting with a Lyme expert. I have now seen too many people, including our son, who are not able to find a Dr. to help them. Maybe Lyme has nothing to do with your problems, but if it does, the Lyme expert is the only one who has knowledge to treat it successfully. ABX treatment alone will not be successful unless the Lyme is in it's first stage. Good luck to you all.