Plaquenil & Low Dose Naltrexone

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New Member

Date Joined Dec 2013
Total Posts : 3
   Posted 12/8/2013 8:33 PM (GMT -6)   
Does anyone take plaquenil and LDN? I recently flared after taking 1 plaquenil a week for a few years. Now taking 2 a day again, 3 weeks in and not feeling better yet. Extreme cognitive dysfunction and I can't work. My dr prescribed the low dose naltrexone to me but I'm afraid to take it. I don't understand if it would interfere with Plaquenil - and I've read it makes some people get worse. I'm so sick that if I got worse I would think it's the LDN fault.. I don't know what to do. Anyone?

Elite Member

Date Joined Jul 2009
Total Posts : 14475
   Posted 12/8/2013 9:12 PM (GMT -6)   
Have you done the drug interaction checker at

It can tell if they have any trouble with interactions.
Lupus, Fibromyalgia, Glaucoma, Asthma, Hypothyriodism, Sleep Apnea, OA, Depression, Allergies, and benign familia tremors

When life throws you lemons....
Pick them up and throw them right back at them! :))

New Member

Date Joined Dec 2013
Total Posts : 1
   Posted 12/10/2013 1:21 PM (GMT -6)   
I haven't heard of anyone getting worse while taking Low Dose Naltrexone. The most often reported side effects are sleep disturbances and vivid dreams, which most often go away after a short time. However, I understand that Plaquenil does have some devastating "side effects," including possible blindness! You should speak with the doctor who prescribed LDN for you. What does he or she say? Very curious. (By the way, I did lots of research on LDN <snip>)

Also, make sure your doctor uses one of the recommended pharmacies to compound the LDN:

Hope this helps.
Julia Schopick

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Post Edited By Moderator (Lynnwood) : 12/10/2013 12:45:39 PM (GMT-7)

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