I can totally relate. Diagnosed with SLE over 3 years ago. I have never had a positive ANA or any other test. Little to no relief from Plaquenil. Prednisone helps as do narcotics. But I can't survive on them. Having a very hard time finding a rheum that will accept my insurance and PCP wont prescribe anymore Plaquenil. They just say go to ER. Then to top it off they just dx'd me with Young Parkinson's. But, from what I've been told and read, only 60% of people withe SLE have any positive labs. I don't get it. I have about
11 out of 14the criteria for SLE and have had 4 different opinions.