Hi! I have all sorts of rashes from lupus-hives, vascular lesions, vasculitis, pemphigoid, discoid and even cutaneous porphyria and of course solar urticaria. It sounds to me like you have a hypersensitivity reaction-called hypersensitivity vasculitis. It's EXTREMELY itchy-the hives are on top and under the skin. When I get them I bleed at the touch of them-here's a link: http://emedicine.medscape.com/article/1083719-overview I read the above on cryoglobulonemia-and I don't think that's it-it's too systemic-and you seem to have localized skin trouble. Just a thought.
Also-make sure your not allergic to the PUPPY. What did the biopsy say?
I can tell you that I take anti-histamines for it (strong prescribed ones)-use steroid creams (very strong prescribed ones like betamethazone) and even have steroid shots INTO them. If an anti-biotic worked for you there could have also been a secondary infection but it isn't likely that hives started from an infection. That's not the process which start hives.
Post Edited (Jujubeee714) : 5/4/2014 3:30:04 PM (GMT-6)